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Caffeine-ethanol mixture fails to constrict cerebral arterioles in vivo. Averaged pial arteriolar diameter (as percentage of diameter before drug application) in response to carotid artery infusion of 50 mM ethanol, 10 µM caffeine, or their combination. Each data point represents an average of no fewer than three animals. *Different from administration of 50 mM ethanol (P < 0.05).
