Table 1.
Baseline and hospital characteristics of hospital survivors censored at 90 days
| Characteristics | IHD (n=353) | CRRT (n=285) | All (n=638) | P Valuea |
|---|---|---|---|---|
| Age, yr | <0.01 | |||
| 18–44 | 70 (19.8) | 74 (26) | 144 (22.6) | |
| 45–64 | 139 (39.4) | 131 (46) | 270 (42.3) | |
| 65–74 | 79 (22.4) | 49 (17.2) | 128 (20.1) | |
| ≥75 | 65 (18.4) | 31 (10.9) | 96 (15) | |
| Men | 203 (57.5) | 167 (58.6) | 370 (58) | 0.81 |
| Race | 0.43 | |||
| White | 250 (70.8) | 212 (74.4) | 462 (72.4) | |
| Black | 33 (9.3) | 19 (6.7) | 52 (8.2) | |
| Other | 70 (19.8) | 54 (18.9) | 124 (19.4) | |
| Body mass index, kg/m2 | 27.1 (23.8–33.8) | 27.7 (23.5–33) | 27.5 (23.7–33.5) | 0.94 |
| Comorbid condition | ||||
| Cardiac disease | 15 (4.2) | 8 (2.8) | 23 (3.6) | 0.40 |
| Chronic renal disease | 26 (7.4) | 9 (3.2) | 35 (5.5) | 0.02 |
| Diabetes | 48 (13.6) | 44 (15.4) | 92 (14.4) | 0.57 |
| Liver transplant | 20 (5.7) | 21 (7.4) | 41 (6.4) | 0.42 |
| Multiple comorbidities | 125 (35.4) | 94 (33) | 219 (34.3) | 0.56 |
| Surgical admission | 210 (65.8) | 199 (73.7) | 409 (69.4) | 0.04 |
| Reference creatinine, mg/dl | 1 (0.8–1.4) | 1 (0.8–1.2) | 1 (0.8–1.2) | 0.02 |
| Maximum KDIGOb | 0.001 | |||
| No AKI | 8 (2.3) | 3(1.1) | 11 (1.7) | |
| Stage 1 | 11 (3.1) | 2 (0.7) | 13 (26) | |
| Stage 2 | 22 (6.3) | 43 (15.1) | 65 (10.2) | |
| Stage 3 | 311 (88.4) | 237 (83.2) | 548 (86) | |
| CSSc,d | 79 (63.3–100.8) | 86 (62.5–115) | 82 (63–108) | <0.01 |
| Severity of hypotensionc,e | 0 (0–6) | 2.7 (0–22.2) | 0 (0–6.4) | <0.001 |
| Fluids, Lc | 2.6 (0.4–4.8) | 4.7 (2.7–7.8) | 3.6 (1.4–6.4) | <0.001 |
| Suspected sepsisc | 93 (26.3) | 109 (38.2) | 202 (31.7) | 0.002 |
| Vasopressorsc | 129 (36.5) | 159 (55.8) | 288 (45.1) | <0.001 |
| Mechanical ventilationc | 220 (62.3) | 211 (74) | 431 (67.6) | 0.002 |
Data are presented as n (%) or median (quartile 1–quartile 3) unless otherwise indicated. There were missing values for age (34 patients), body mass index (747 patients), surgical admission (49 patients), maximum Kidney Disease Improving Global Outcomes (KDIGO; one patient), computerized severity score (CSS; one patient), and severity of hypotension (nine patients).
P value for the comparison of intermittent hemodialysis (IHD) and continuous RRT (CRRT) groups.
Measured before RRT initialization.
Measured within 24 hours after intensive care unit admission.
Information in Materials and Methods.
Area under the curve for severity and duration of hypotension (Materials and Methods).