Table 2.

Logistic regression model for continuous RRT

Outcome: Continuous RRT	Odds Ratio	Upper 95% Confidence Interval	Lower 95% Confidence Interval	P Valuea
Age (by 5 yr)	0.94	0.9	0.98	0.004
Men	0.92	0.72	1.19	0.54
Race
Black versus white	1.41	0.79	2.49	0.24
Other versus white	1.26	0.76	2.09	0.38
Cardiac disease	0.58	0.3	1.11	0.10
Chronic renal disease	0.43	0.24	0.76	0.004
Diabetes	1.14	0.76	1.69	0.53
History of liver transplant	0.99	0.59	1.67	0.97
Multiple comorbidities	1.2	0.87	1.66	0.28
Surgical admission	1.19	0.91	1.57	0.21
Reference creatinine	0.86	0.75	0.98	0.03
KDIGO stage 3 before RRTb	0.6	0.41	0.87	<0.01
Computerized severity scorec	1	1	1.01	0.85
Severity of hypotension (by 10)d,e	1.1	1.04	1.16	0.001
Fluids, Ld	1.15	1.1	1.19	<0.001
Suspected sepsisd	1.39	1.04	1.84	0.02
Vasopressorsd	1.86	1.4	2.47	<0.001
Mechanical ventilationd	0.77	0.56	1.05	0.10

n=1245. KDIGO, Kidney Disease Improving Global Outcomes.

^aP value for the comparison of intermittent hemodialysis and continuous RRT groups.

^bMeasured before RRT initialization.

^cInformation in Materials and Methods.

^dMeasured within 24 hours after intensive care unit admission.

^eArea under the curve for severity and duration of hypotension (Materials and Methods). Severity of hypotension was measured using a hypotensive index, which integrates the duration and depth of systolic BP<90 mmHg in the first 24 hours after intensive care unit admission. Points are defined as a lowering of BP<90 mmHg over a time interval of 24 hours: i.e., a BP of 80 mmHg for 1 hour and a BP≥90 mmHg for 23 hours will result in 10 points ([90−80]×1=10); a BP of 85 mmHg for 10 hours and a BP≥90 mmHg for 14 hours will result in 50 points ([90−85]×10=50).