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. 2016 Jan;22(1):25–35. doi: 10.1177/1352458515579445

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© The Author(s), 2015

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 3.0 License (http://www.creativecommons.org/licenses/by-nc/3.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page(https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 4. — Neuronal cell counts ((a), (c)) and GAD-67+ interneuron cell counts ((b), (d)) were performed in six patients with MS and seizures and six individuals with MS alone in each layer of the precentral ((a), (b)) and middle temporal gyrus ((c), (d)) and compared to six control cases. All cases were randomly chosen and analysed blinded to case identification. The percentage of reduction in counts compared to controls is shown (mean ± SE). There is a significant (*p < 0.001) reduction in the numbers of neurons and interneurons in layers IV and VI of the middle temporal gyrus. MS: multiple sclerosis.