Table 2.
GML numbers in the precentral, superiori frontal and middle temporal cortex subdivided into Type I and Type III lesions in MS patients with seizures (n = 21) and with MS alone (n = 30).
| n | Precentral |
Superior frontal |
Middle temporal |
|
|---|---|---|---|---|
| gyrus | gyrus | gyrus | ||
| GMLs of all types present in each patient (%) | ||||
| MS | 30 | 22 (73) | 26 (87) | 23 (77) |
| MS + seizures | 21 | 11 (52) | 16 (76) | 21 (100)a |
| Type I GMLs present in each patient | ||||
| MS | 30 | 11 | 12 | 9 |
| MS + seizures | 21 | 5 | 6 | 14b |
| Type III GMLs present in each patient | ||||
| MS | 30 | 21 | 13 | 13 |
| MS + seizures | 21 | 7 | 9 | 8 |
Lesions were seen in the middle temporal gyrus in 100% of those with MS and seizures, a significant increase above those with MS alone (Fisher’s test, ap < 0.032). A significant increase in Type I GMLs but not Type III GMLs in the middle temporal gyrus was seen in those with seizures compared to those with MS alone (bFisher’s test, p < 0.01) whereas there was no difference in the frequency of Type III GMLs. GML: grey matter lesion; MS: multiple sclerosis.