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. 2015 Jun 20;13:42. doi: 10.1186/s12915-015-0153-1

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© Luo et al. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Dynamic changes of abnormal lung structure in Apc CKO lungs. There was no significant histological difference in E11.5 lungs between WT and Apc CKO mice. Aggregative growth of mesenchymal cells in Apc CKO lungs was apparent from E12.5. Lung tissue (arrowheads) was interspersed with massive areas of hemorrhage at E14.5