Table 1.
Characteristics | Total | Low AMH <1.0 ng/mL | Normal AMH 1.0–3.5 ng/mL | High AMH >3.5 ng/mL | P Value |
---|---|---|---|---|---|
n, % | 1202 | 124 (10.3) | 595 (49.5) | 483 (40.2) | |
Age, y | 28.7 ± 4.8 | 32.8 ± 5.1 | 29.1 ± 4.6 | 27.3 ± 4.2 | <.001 |
BMI, kg/m2 | 26.3 ± 6.6 | 27.2 ± 7.2 | 26.5 ± 6.5 | 25.9 ± 6.5 | .14 |
Race | .79 | ||||
White | 1138 (94.7) | 119 (96.0) | 563 (94.6) | 456 (94.4) | |
Nonwhite | 64 (5.3) | 5 (4.0) | 32 (5.4) | 27 (5.6) | |
Marital status | .28 | ||||
Married | 1101 (91.6) | 109 (87.2) | 553 (92.9) | 439 (90.9) | |
Living with partner | 72 (6.0) | 12 (9.7) | 30 (5.0) | 30 (6.2) | |
Other | 29 (2.4) | 3 (2.4) | 12 (2.0) | 14 (2.9) | |
More than high school education | 1038 (86.4) | 107 (86.3) | 514 (86.4) | 417 (86.5) | .99 |
Treatment | |||||
LDA | 602 (50.1%) | 67 (54.0) | 286 (48.1) | 249 (51.6) | |
Placebo | 600 (59.9%) | 57 (46.0) | 309 (51.9) | 234 (48.4) | .34 |
Previous live births | .01 | ||||
0 | 561 (46.7) | 55 (44.4) | 255 (42.9) | 251 (52.0) | |
1 or 2 | 641 (53.3) | 69 (55.6) | 340 (57.1) | 232 (48.0) | |
Number of previous pregnancy losses | .67 | ||||
1 | 804 (66.9) | 82 (66.1) | 392 (65.9) | 330 (68.3) | |
2 | 398 (33.1) | 42 (33.9) | 203 (34.1) | 153 (31.7) | |
Gestational age of most recent loss, wk | 9.2 ± 4.9 | 9.2 ± 4.5 | 9.1 ± 4.7 | 9.4 ± 5.3 | .58 |
Time from last loss to randomization, mo | .34 | ||||
≤4 | 630 (53.3) | 69 (56.1) | 312 (53.4) | 249 (52.4) | |
5–8 | 211 (17.9) | 25 (20.3) | 90 (15.4) | 96 (20.2) | |
9–12 | 103 (8.7) | 8 (6.5) | 56 (9.6) | 39 (8.2) | |
>12 | 238 (20.1) | 21 (17.1) | 126 (21.6) | 91 (19.2) |
P value from ANOVA or χ2 test, except for cases of cell size less than five (marital status only). Information was missing for AMH (n = 26), BMI (n = 20), education (n = 1), gestational age of most recent loss (n = 161), and time from last loss to randomization (n = 20).