Table 3.
Association Between AMH and Fecundability Stratified by Age Group (<35 y and ≥ 35 y)
| hCG pregnancy |
Clinical pregnancy |
|||||
|---|---|---|---|---|---|---|
| Low AMH <1.0 ng/mL | Normal AMH 1.0–3.5 ng/mL | High AMH >3.5 ng/mL | Low AMH <1.0 ng/mL | Normal AMH 1.0–3.5 ng/mL | High AMH >3.5 ng/mL | |
| Participants < 35 y of age (n = 1062) | ||||||
| Achieved pregnancy, n, % | 54 (71.1) | 340 (64.4) | 300 (65.6) | 49 (64.5) | 310 (58.7) | 276 (60.3) |
| FOR, unadjusted | 1.22 (0.87, 1.70) | Referent | 1.09 (0.91, 1.30) | 1.15 (0.82, 1.62) | Referent | 1.08 (0.90, 1.30) |
| FOR, adjusted modela | 1.24 (0.89, 1.73) | Referent | 1.07 (0.90, 1.29) | 1.17 (0.83, 1.64) | Referent | 1.07 (0.89, 1.29) |
| FOR, adjusted model 2b | 1.26 (0.90, 1.76) | Referent | 1.06 (0.88, 1.27) | 1.17 (0.83, 1.65) | Referent | 1.05 (0.87, 1.27) |
| Participants ≥ 35 y of age (n = 140) | ||||||
| Achieved pregnancy, n, % | 28 (58.3) | 43 (64.2) | 15 (60.0) | 25 (52.1) | 25 (52.1) | 14 (56.0) |
| FOR, unadjusted | 0.84 (0.49, 1.42) | Referent | 0.95 (0.49, 1.83) | 0.84 (0.49, 1.46) | Referent | 1.02 (0.52, 2.01) |
| FOR, adjusted model 1a | 0.93 (0.53, 1.62) | Referent | 0.97 (0.50, 1.88) | 0.89 (0.50, 1.58) | Referent | 1.03 (0.52, 2.03) |
| FOR, adjusted model 2b | 0.88 (0.48, 1.60) | Referent | 1.06 (0.50, 2.24) | 0.81 (0.43, 1.51) | Referent | 1.08 (0.5, 2.34) |
FORs are presented as estimate (95% confidence interval).
a
Adjusted for age.
b
Adjusted for age, race, BMI, treatment, income, parity, number of previous losses, and time from last loss to randomization.