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D-4F-treatment increased PCN neurite/axonal outgrowth and IGF1 mediated D-4F-treatment induced neurite/axonal outgrowth; D-4F-treatment did not increase OPC proliferation but decrease OPC death after stroke. Neurite-outgrowth (A), axonal-outgrowth (B), OPC MTS and LDH (C) assays and quantitative data.
