TABLE 1.
Heavy and light particle yields
| Virus | Lighta | Heavya | Heavy/lightb | Mixturea |
|---|---|---|---|---|
| WTc | 8.8 × 1011 | 3.3 × 1012 | 3.8 | 1.1 × 1012 |
| G33A | 9.4 × 1011 (0.9) | 7.7 × 1011 (4.3) | 0.8 | 1.5 × 1012 (0.7) |
a
Values are the total heavy and light particle yields from the cesium chloride gradients and the heavy/light particle mixture from the Virabind column. It is important to note the intrinsic variability associated with syringe extraction of virus bands from cesium chloride gradients, and total particle yields are approximations. Numbers in parentheses indicate the fold reduction in G33A mutant particle yield compared to wild-type virus for each of the categories.
b
Heavy/light indicates the ratio of heavy to light particles produced for each of the viruses.
c
WT, wild type.