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. 2015 Dec 30;90(2):813–828. doi: 10.1128/JVI.01942-15

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Copyright © 2015 Schiffner et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license.

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FIG 4 — Negative-stain EM and DSC analysis of unmodified and cross-linked, antibody-selected BG505 trimers. 2D class averages are shown for GLA cross-linked and PGT145 positively selected (GLA +PGT145) (A), GLA cross-linked and PGT151 positively selected (GLA +PGT151) (B), EDC cross-linked and PGT145 positively selected (EDC +PGT145) (C), EDC cross-linked and 3VC315 positively selected (D), GLA cross-linked and 19b negatively selected (E), and EDC cross-linked and 19b negatively selected (F) trimers. (G) DSC analysis of GLA cross-linked BG505 trimers positively selected on PGT151.