FIG 5.

Inferred phylogenetic relationship among GAS strains recovered in Thunder Bay from invasive disease cases and from cases of severe soft tissue infection. Neighbor-joining phylogenetic trees for each of emm82 (A), emm83 (B), emm87 (C), emm101 (D), emm114 (E), and emm4 (F) strains were constructed using nonredundant, whole-genome single-nucleotide polymorphism (SNP) loci (emm82, 56 SNPs; emm83, 259 SNPs; emm87, 59 SNPs; emm101, 29 SNPs; emm114, 12 SNPs; emm4, 7 SNPs) identified against their corresponding reference genomes. Strains from 2011 are depicted in orange, those from 2012, in purple, and those from 2013, in gray. See the supplemental material for details about methods.