Table 4. Content changes since our 2014 publication (6). Only those major categories that could be normalised for comparison between 2013 and 2015 are included.

	Oct 2013	2015	Percentage increase
Target protein IDs	2485	2761	11
Ligands total	6064	8024	32
Approved drugs	559	1233	121
Antibodies	10	138	1280
Peptides	1776	1981	12
Synthetic small molecules	3504	5055	44
PubChem SIDs	3107	8024	158
PubChem CIDs	2694	6037	124
Binding constants	41076	44691	9
References	21774	27880	28