Table 2. Expression and methylation during erythropoiesis.
| HSC | CMP | CFU-E | ERY | Common | |
|---|---|---|---|---|---|
| mRNA | |||||
| Expressed | 3508 | 5366 | 3836 | 7458 | 297 |
| Methylated | 18437 | 16094 | 10337 | 12923 | 9549 |
| Methylated and Expressed | 2937 | 4045 | 1658 | 4417 | 133 |
| Methylated and Not Expressed | 15500 | 12049 | 8679 | 8506 | 9416 |
| Not Methylated but Expressed | 571 | 1321 | 2178 | 3041 | 164 |
| Not Methylated and Not Expressed | 1268 | 1753 | 9040 | 2832 | 13367 |
| ncRNA | |||||
| Expressed | 40 | 81 | 39 | 203 | 4 |
| Methylated | 1025 | 842 | 473 | 594 | 429 |
| Methylated and Expressed | 25 | 51 | 18 | 91 | 0 |
| Methylated and Not Expressed | 1000 | 791 | 455 | 503 | 429 |
| Not Methylated but Expressed | 15 | 30 | 21 | 112 | 4 |
| Not Methylated and Not Expressed | 2162 | 2304 | 2715 | 2430 | 2794 |
Expression is determined by microarray andRNA-Seq expression profiles. Methylation is defined as the number of transcripts with a DNA methylation signal in the promoter. We have annotated a complete set of 23 213 mRNA transcripts and 3227 lncRNAs based on (38).