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. 2015 Dec 15;44(Database issue):D184–D189. doi: 10.1093/nar/gkv1309

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© The Author(s) 2015. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 1. — Individual gene page for human tRNA-Val-AAC-4–1. (A) Direct link to the genomic locus of the tRNA gene with the display of related data tracks in the UCSC Genome Browser (3) is provided when available. Top scoring isotype-specific models are included to illustrate consensus (or lack thereof) in isotype classification. The rank of Val-AAC-4–1 indicates that it is the fourth highest scoring out of six human Val-AAC tRNA genes. An atypical feature for the displayed tRNA is G50:G64, a non-Watson-Crick base pair mismatch in the T-arm. Known modifications of the tRNA were retrieved from MODOMICS (18). (B) Expression of tRNA fragments derived from tRNA-Val-AAC using ARM-Seq were retrieved from published literature (13). (C) Graphic representation of tRNA secondary structure prediction from tRNAscan-SE was rendered by NAVIEW (22). Secondary structure fold using minimum free energy was generated by RNAfold (17). (D) Multiple sequence alignments of tRNA genes with the same isotype are shown with the stems highlighted and individual scores. (E) Variants from dbSNP (19) build 142 located at the tRNA-Val-AAC-4–1 locus are listed with their relative tRNA positions, alternate alleles, commonality, predicted effects and direct links to the dbSNP website for further information.