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. 2015 Dec 14;112(52):16042–16047. doi: 10.1073/pnas.1514250112

Fig. S5.

Fig. S5.

Differences in aerobic capacity and markers of mitochondrial biogenesis are minimal in sedentary WT and Ostn-KO mice. (A) Summary statistics for trend of oxygen consumption over time of sedentary WT and Ostn-KO mice upon initiation of treadmill exercise at time 0 (all points NS for WT vs. Ostn-KO). (B) Representative electron micrographs of longitudinal tibialis anterior sections from sedentary mice. (C) Summary statistics for mitochondrial content by weight in gastrocnemius isolates of sedentary mice. *P < 0.05 vs. WT. (D and E) Representative Western blots of respiratory chain enzymes and GAPDH (D) and summary statistics for respiratory complex expression normalized to GAPDH in gastrocnemius (E) of sedentary WT and Ostn-KO mice. (F and G) Representative stains for SDH activity of tibialis anterior cross-sections (F) and summary statistics for percent area of cross-sections (G) stained for SDH activity in sedentary WT and Ostn-KO mice. *P < 0.05 vs. WT. KO, Ostn-KO; Sed, sedentary.