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. 2015 Dec 7;112(52):15940–15945. doi: 10.1073/pnas.1521818112

Fig. 4.

Fig. 4.

An ancient genetic module underlies the pro- and mesopterygium. (A–D) The 3′Hox gene expression patterns at stage 30. Each gene is expressed in the anterior mesenchyme. The expression domain is limited to only a narrow strip underlying the ectoderm. (E) Hoxa5 in the pectoral fin of the shark (C. plagiosum), where expression is in the anterior and posterior fin mesenchyme. (F and G) Fgf7 expression at stage 30 and 31. (H and I) Wnt3 expression 1 d after the implantation of DMSO (H) or FGF7 beads (I). (J and K) Wnt3 in situ hybridization in the pectoral fin at stage 31 following DMSO (J) or SU5402 (K) injection into the anterior fin. (L and M) Alcian Blue staining following DMSO or SU5402 injection into the anterior fin. The tip of the pectoral fin regressed in SU5402 injection (arrowheads).