. 2015 Dec 11;112(52):16048–16053. doi: 10.1073/pnas.1521675112

Table 2.

Mutations in MED16 cause resistance to cellulose biosynthesis inhibitors

Growth inhibition
Line	Isoxaben, nM	DCB, nM	Indaziflam, pM
WT	2.81 ± 0.21^A	102 ± 8^A	220 ± 10^A
cob-6	0.53 ± 0.07^B	57 ± 2^B	167 ± 7^B
sfr6-3	3.11 ± 0.15^C	138 ± 8^C	274 ± 11^C
mon1 cob-6	2.58 ± 0.14^D	92 ± 5^D	198 ± 9^D
sfr6-3 cob-6	2.51 ± 0.12^D	88 ± 7^D	191 ± 7^D

Root length of seedlings grown on vertically oriented agar plates with various concentrations of the inhibitors for 7 d was measured. GI50 is the concentration of drug that leads to 50% inhibition of root length relative to the growth of the line on agar without inhibitors. For statistical analysis, we performed ANOVA-coupled Tukey test on the raw data. The values are the means ± SE (n = 50).