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5hmC accumulates in differentiated tonsil epithelium but not in NPCs. (A) 5hmC level was assessed by IHC in normal tonsil epithelium; the undifferentiated basal cell layer is outlined. (B) 5hmC IHC (Left) and EBER in situ hybridization (Right) staining of two representative EBV+ NPCs. EBV-positive cells are outlined on Left. (C) 5hmC staining of telomerase-immortalized NOKs cells differentiated in air-interface cultures. Original magnification of all figures, 40×.
