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. Author manuscript; available in PMC: 2016 Jan 6.
Published in final edited form as: JAMA Surg. 2015 Apr;150(4):299–306. doi: 10.1001/jamasurg.2014.2881

Table 3.

Three-Year Conditional Disease-Free Survival From Years 0 to 5 After Surgery

Variable 3-y Conditional Disease-Free Survival, %
0 y 1 y 2 y 3 y 4 y 5 y
Modified NIH criteria
 Very low risk 91 92 92 92 100 100
 Low risk 95 91 90 90   97 100
 Intermediate risk 95 90 92 94   92   79
 High risk 65 68 71 85   83   94
MSKCC GIST nomogram
 Quartile 4 91 92 92 92 100 100
 Quartile 3 95 91 90 90   97 100
 Quartile 2 94 90 91 95   92   79
 Quartile 1 62 65 68 83   82   94
Tumor size, cm
 <5.0 95 92 92 92   98 100
 5.0–10.0 80 78 80 88   89   85
 >10.0 62 64 69 83   81   90
Tumor site
 Gastric 85 85 88 93   91   90
 Nongastric 78 74 69 77   87 100
Mitotic rate, per 50 HPFs
 ≤5 93 91 91 92   94   91
 6–10 85 88 88 92   92 100
 >10 48 50 55 74   69   83

Abbreviations: GIST, gastrointestinal stromal tumor; HPFs, high-power fields; MSKCC, Memorial Sloan Kettering Cancer Center; NIH, National Institutes of Health; TKI, tyrosine kinase inhibitor.