Table 1. Pathologic and molecular features of gliomas with NF1/Ch17 loss.
NF1/Ch17loss n= 5 | Ch17 intact n = 125 | |
---|---|---|
Glioma subtype | GBM 5/5 (100%) | 81/125 (65%) |
Adult GBM 4/5 | 53/125 (42%) | |
Pediatric GBM 1/5 | 28/125 (22%) | |
Diffuse (II-III) (0) | 44/125 (35%) | |
Podoplanin IHC | 4/5 | 55/122 (45%) |
EGFR amp | 0/4 | 17/90 (19%) |
p53 IHC | 1/5 | 32/96 (33%) |
IDH1 (R132H) IHC | 0/5 | 37/125 (30%) |