Table 2.
Primary, Secondary and Safety Outcomes
Outcome | CT (%) (n=200) |
MPI (%) (n=200) |
% Difference* (95% CI) |
P |
---|---|---|---|---|
Cardiac catheterization within 1 year |
30 (15) | 32 (16) | −1.0 (−8.5, 6.5) | 0.89 |
Cardiac catheterization without revascularization within 1 year |
15 (7.5) | 20 (10) | −2.5 (−8.6, 3.5) | 0.41 |
CABG within 1 year | 7 (4) | 1 (0.5) | 3.0 (−0.3, 6.9) | 0.068 |
PCI within 1 year | 8 (4) | 11 (5.5) | −1.5 (−6.4, 3.3) | 0.64 |
Median length of stay in hours (IQR) |
28.9 (11.0, 48.4) |
30.4 (23.9, 51.3) |
0.057 | |
Serious complications of imaging |
0 | 0 | 0 (−2.4, 2.4) | 1 |
Serious complications of revascularization† |
3 (2) | 1 (0.5) | 1.0 (−1.9, 4.2) | 0.62 |
All-cause death | 1 (0.5) | 6 (3) | −2.5 (−6.3, .7) | 0.122 |
Non-fatal MACE ‡ | 9 (5) | 9 (5) | 0 (−4.7, 4.7) | 1 |
Death + MACE § | 9 (5) | 15 (7.5) | −3.0 (−8.3, 2.2) | 0.29 |
CABG, coronary artery bypass grafting; CI, confidence interval; CT, coronary computed tomography angiography; IQR, inter-quartile range; MACE, major adverse cardiovascular events (consisting of myocardial infarction, stroke and cardiac arrest); MPI, radionuclide stress myocardial perfusion imaging; PCI, percutaneous coronary intervention
% Difference equals proportion in the MPI arm minus proportion in the CT arm
Two CT patients had complications after coronary artery bypass grafting (one sternal wound infection and one prolonged mechanical ventilation). One MPI patient had coronary artery dissection during percutaneous intervention. One CT patient had coronary artery perforation during percutaneous intervention for a subsequent acute myocardial infarction.
Two MPI patients each had two separate cerebrovascular accidents.
One CT patient had a non-fatal myocardial infarction and later died.