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. 2016 Jan 6;12(1):e1005372. doi: 10.1371/journal.ppat.1005372

Table 1. Expression of TIGIT and PD-1 on ATL cells and HTLV-1 infected CD4+ T cells.* .

Disease Type TIGIT- PD1- TIGIT+ PD1- TIGIT- PD1+ TIGIT+ PD1+
ATL #1 (c) 0.06 0.61 1.91 97.4
ATL #2 (c) 7.38 4.38 19.6 68.6
ATL #3 (c) 0.31 21.3 0.15 78.3
ATL #4 (a) 51.2 39.8 2.66 6.38
ATL #5 (a) 2.69 1.76 1.76 93.8
HAM/TSP #1 17.8 18.9 12.0 51.3
HAM/TSP #2 34.5 30.2 14.3 21.1
HAM/TSP #3 13.2 19.9 15.6 51.2
HAM/TSP #4 18.1 13.6 12.6 55.7
HAM/TSP #5 20.8 24.1 11.9 43.2
Healthy donors 75.3 ± 8.91 3.09 ± 1.05 13.8 ± 3.73 7.89 ± 4.44

*For acute ATL cases, the numbers indicate the percentage of CD3lowCD4+ ATL cells in each category. For HAM/TSP cases, the numbers indicate the percentage of CD4+CADM1+ T cells. In healthy donors, the numbers indicate the percentage of CD4+ T cells. The mean percentages (± SD) from 4 donors are shown for healthy donors.

(a): acute ATL,

(c): chronic ATL.