Table 1. Initial conditions and baseline parameters, with parameter ranges given in parentheses.

Parameter	Meaning	Value	Source
c	viral clearance rate	23 day−1 (23 day−1–100 day−1)	lower: [35] upper: [36]
δ	productively infected cell death rate	1 day−1	[37]
p	viral production rate	50000 per day (1000–50 000 per day)	lower: [38], upper: [39]
ε	drug efficacy	0.99 (0.9–0.999)	See text
T	target cell density (assumed constant)	800 cells per μL
$t_{1/2}^L$	Net latent reservoir half-life	44 months	[10]
η 1	Latent reservoir decay rate in the absence of replenishment by de novo infection	5.17 × 10−4 day−1; half-life is ln(2)/η 1 = 44.0 mos	See text
L 0	Initial latent reservoir size	1 per 106 cells ≈ 0.8 cells per mL	[40]
V 0	Initial viral load	3.1 copies/mL	[2]
a	Latent cell activation rate	1.74 × 10−3 day−1	See text