. Author manuscript; available in PMC: 2016 Jan 6.

Published in final edited form as: ACS Sustain Chem Eng. 2014 Apr 18;2(7):1691–1698. doi: 10.1021/sc500153k

Table 3.

Differential Cell Counts in Blood of Mice Exposed to Suspension (CNCS) and Powder (CNCP) Forms of Cellulose Nanocrystals^a

per 2 × 10⁵ total cells	red blood cells	basophils	PMNs	eosinophils	lymphs	total WBCs
control	199,975.9 ± 4.5	9.7 ± 1.9	1.5 ± 0.6	0 ± 0	12.8 ±2	24 ± 4.5
CNCP (200 µg)	199,935.7 ± 8.8	26.8 ± 0.9^*	11.3 ± 1.2^*	3.6 ± 0.8^*	22.6 ± 6^*	64.3 ± 8.9^*
CNCS (200 µg)	199,922.9 ± 5.7	32.3 ± 1.4^*,^α	11.9 ± 1.6^*	4.5 ± 0.7^*	28.3 ± 3.4^*	77 ± 7.1^*

The relative number of each type of white blood cell (WBC) was estimated by normalizing the total cells in each case to 2 × 10⁵ cells. The data are presented as mean ± SE (n ≥ 3).

p < 0.05 vs control (water treated) mice.

^α

p < 0.05 vs mice exposed to CNCP particles.