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. 2016 Jan 6;10(1):e0004300. doi: 10.1371/journal.pntd.0004300

Fig 7. Suggesting targets for orphan compounds: alanyl aminopeptidase.

Fig 7

A series of 13 structurally related orphan compounds (EC50 values range = 0.03–0.74 uM against P. falciparum, data from [50], available at TDR Targets) are connected in our network model to the PfA-M1 Plasmodium enzyme. In the figure we show the Markush structure for the series, and the corresponding R-groups and their database IDs. We also show one representative of other active similar compounds (see [95]) with activity against defined targets in the network.