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. 2016 Jan 6;11(1):e0144973. doi: 10.1371/journal.pone.0144973

Table 2. Number of patients enrolled in completed pediatric phase 3 epilepsy clinical trials.

Number of patients enrolled (N = 27,587) Median size of the trial (IQR)
Published trials 21,123 (77%) (N = 75 trials with available data) 207 (IQR 97 to 298)
*20,575 (82%)(N = 74 trials with available data *206 (IQR 98 to 396)
Unpublished trials 6,464 (23%)(N = 32 trials with available data) 97.5 (IQR 45 to 286)
*4,437 (18%) (N = 24 trials with available data) *85 (IQR 51 to 204)

*Trial was completed before 2014 (which takes into account the FDAAA deadline to publication of 1 year after completion). FDAAA = Food and Drug Administration Amendments Act of 2007