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. Author manuscript; available in PMC: 2017 Jan 1.
Published in final edited form as: Proteomics. 2015 Nov 24;16(1):33–46. doi: 10.1002/pmic.201500171

Table 1. Proteins upregulated with BLM treatment and associated with each of the enriched profibrotic pathways.

Profibrotic enriched pathways Proteins upregulated with BLM treatment
PI3K/AKT signaling MTOR, HSP90B1, ITGA3, RRAS2, HSP90AB1, INPP5B, SOS2, TSC2, HSP90AA1, INPPL1, NOS3, OCRL
Epithelial adherens junction signaling MYH4, MYH6, RRAS2, MYH13, SORBS1, MYO7A, MYH3, MYL4, IQGAP1, PTPRM, NOTCH1, APC
Nitric oxide signaling HSP90B1, HSP90AB1, RYR2, GUCY2F, CACNA1C, HSP90AA1, NOS3, ATP2A2, ATP2A1
IL-4 signaling MTOR, RRAS2, INPP5B, SOS2, INPPL1, NFATC4, OCRL
Endothelin-1 signaling RRAS2, GNA15, PLB1, GPLD1, PLA2R1, GNA11, GUCY2F, PLCL2, NOS3, ADCY10