Table 3. Proteins upregulated with VEGF inhibitor treatment and associated with each of the enriched antifibrotic pathways.
Antifibrotic enriched pathways | Proteins upregulated with VEGF inhibitor treatment |
---|---|
Natural killer cell signaling | PAK6, SOS1, SH3BP2, INPP5D |
PTEN signaling | FLT1, SOS1, KDR, INPP5D |
Intrinsic prothrombin activation pathway | FGG, COL3A1 |
Gap junction signaling | SOS1, PLCD4, HTR2A, MAP3K2 |
Endothelin-1 signaling | RIPK1, SOS1, MAP3K2 |