Skip to main content
. Author manuscript; available in PMC: 2016 May 18.
Published in final edited form as: Leukemia. 2015 Aug 12;30(1):219–228. doi: 10.1038/leu.2015.222

Figure 2. AUY922 treatment induces apoptosis in T-ALL cell lines.

Figure 2

T-ALL cell lines were treated with DMSO or 30 nM of AUY922 for 72 h, and assessed for apoptosis by flow cytometric analysis following Annexin V-FITC and PI double staining. Early and late apoptosis represent the fraction of Annexin V-positive / PI-negative cells and Annxin V-positive / PI-positive cells, respectively. Values are mean ± s.d. percentages of Annexin V-positive cells in triplicate experiments. *, P < 0.05; **, P < 0.01; ***, P < 0.001 by two-sample, two-tailed t test. The representative dot plots images in this assay are shown in Supplementary Figure 1.