Table 2.

Pain medication use at baseline and risk of symptoms of active inflammatory bowel disease at follow up

Medication	Risk of active Crohn’s disease at follow up (n=572) RR (95% CI)	Risk of active ulcerative colitis at follow up (n=219) RR (95% CI)
Any NSAID**	1.05 (0.82–1.34)	1.13 (0.78–1.63)
NSAID ≥5 x/monthly	1.50 (1.04–2.18)	1.01 (0.49–2.06)
Any acetaminophen	1.21 (1.07–1.38)	1.06 (0.82–1.35)

^*Unadjusted risk ratio and 95% confidence interval for active disease at follow up with use of drug as compared to no use

^**Non-steroidal anti-inflammatory drug