Table 1.
Candidate CNVs discovered in both patient cohorts with Illumina arrays
| Sample | Cytoband | Coordinates (hg19) | Length (bp) | Estimated copy number | Candidate genes within or near CNV | qPCR‐verified CNV? |
|---|---|---|---|---|---|---|
| PG05 | 5q33.3 | 158899789–159627399 | 727,611 | 3 | ADRA1B | Yes |
| HLHS56 | 6p24.1 | 12306232–12320786 | 14,555 | 1 | EDN1 | Yes |
| HLHS24 | 11p15.4 | 10368614–10404266 | 35,653 | 3 | ADM | Yes |
| PG07 | 11q13.2–q13.3 | 68100519–69469069 | 1,368,551 | 3 | CPT1A, IGHMBP2 | Yes |
| HLHS27, HLHS39 | 16q23.3 | 83196349–83209154 | 12,806 | 1 | CDH13 | Yes (39 only) |
| HLHS08 | 1q24.2 | 170560604–170613602 | 52,999 | 1 | PRRX1 | Not tested |
| HLHS57 | 2p21 | 45408893–45974339 | 565,447 | 3 | PRKCE | Not tested |
| HLHS22 | 3p22.3 | 32953920–32985486 | 31,567 | 1 | TRIM71 | Not tested |
| HLHS27 | 7q21.12 | 87524013–87656083 | 132,071 | 3 | ADAM22 | Not tested |
| HLHS44 | 9q21.32–q21.33 | 86881490–87359570 | 478,081 | 3 | NTRK2 | Not tested |
| PG16 | 15q26.1 | 90108613–90171306 | 62,694 | 3 | KIF7 | Not tested |
| HLHS23 | 16q12.2 | 56653745–56694878 | 41,134 | 1 | MT1E, MT1F | Not tested |
| HLHS44 | 17q12 | 32441969–32566206 | 124,238 | 3 | ASIC2, CCL2 | Not tested |
| HLHS23 | 21q21.3 | 27513837–28194874 | 681,038 | 3 | APP | Not tested |
| HLHS23 | 21q21.3 | 28202149–29000785 | 798,637 | 3 | ADAMTS1, ADAMTS5 | Not tested |
| HLHS41 | 21q22.2 | 41034215–41435172 | 400,958 | 3 | DSCAM | Not tested |
The candidate gene(s) may not be the only gene(s) within or near the CNV.