. Author manuscript; available in PMC: 2017 Jan 15.

Published in final edited form as: Bioorg Med Chem. 2015 Nov 28;24(2):113–122. doi: 10.1016/j.bmc.2015.11.038

Table 1.

Antiproliferative activities of 1–3 against human breast cancer cell lines.

Cell line	Meleagrin (1) IC₅₀ μM	Roquefortine C (2) IC₅₀ μM	DHTD (3) IC₅₀ μM
MCF7	1.9	21.7	~40
MCF7-dox	3.2	24.4	23.8
BT-474	2.7	29.6	~40
SKBR-3	2.8	23.4	~40
MDA-MB-231	6.8	23.5	31.8
MDA-MB-468	8.9	28.6	~40
T-47D	>40	ND	ND