Table 1.
Demographic information and comparisons for subjects given placebo (n=25), amphetamine 10 mg (n=18), and amphetamine 20 mg (n=23). Values are means (standard deviations) unless otherwise specified.
| Placebo | Amphetamine 10 mg |
Amphetamine 20 mg |
Group difference test |
|
|---|---|---|---|---|
| Age (years) | 22.9 (4.2) | 22.7 (4.8) | 22.4 (3.9) | F(2,63)<1, NS |
| Years of education |
15.0 (1.8) | 15.9 (2.5) | 15.1 (1.4) | F(2,63)=1.4, NS |
| Gender | 12 Male, 13 Female | 7 Male, 11 Female | 11 Male, 12 Female | Fisher’s Exact<1, NS |
| Body Mass Index (Kg/m2) |
23.2 (2.7) | 23.5 (4.8) | 24.3 (4.6) | F(2,63)<1, NS |
| Baseline systolic blood pressure (mm Hg) |
116.2 (10.2) | 118.4 (10.8) | 122.1 (12.7) | F(2,63)=1.67, NS |
| Baseline diastolic blood pressure (mm Hg) |
73.7 (7.3) | 72.1 (8.7) | 74.7 (7.4) | F(2,63)<1, NS |
| Baseline heart rate (beats/min) |
72.0 (11.0) | 69.8 (11.9) | 73.9 (14.0) | F(2,63)<1 NS |
| Post-test systolic blood pressure (mm Hg) |
125.1 (15.2) | 122.8 (7.3) | 136.5 (11.4) | F(2,63)=6.1, p=0.005*@ |
| Post-test diastolic blood pressure (mm Hg) |
73.8 (13.0) | 74.9 (8.1) | 83.7 (8.4) | F(2,63)=5.0, p=0.01*@ |
| Post-test heart rate (beats/min) |
62.8 (8.1) | 69.1 (8.4) | 75.6 (18.6) | F(2,63)=4.1, p=0.02* |
| Change systolic | 7.3 (14.7) | 2.3 (9.9) | 13.5 (12.0) | F(2,63)=3.0, p=0.06@ |
| Change diastolic | −0.45 (11.2) | 0.42 (9.5) | 9.2 (9.8) | F(2,63)=4.8, p=0.01*@ |
*
p< .05, placebo vs. amphetamine 20 mg.
@
p < .05, amphetamine 10 mg vs. amphetamine 20 mg.
F F-statistic, NS not significant