Table 3.
Effect of increasing mean dose on cognitive test scores by brain volume. P-values are grouped in columns according to the inclusion (+) or exclusion (−) of age in the model.
Normal Tissue Volume | Estimated IQ | WIAT Math | WIAT Reading | WIAT Spelling | ||||
---|---|---|---|---|---|---|---|---|
− | + | − | + | − | + | − | + | |
Entire Brain | 0.0121 | <0.0001 | 0.0096 | 0.0007 | n.s. | <0.0001 | n.s. | 0.0002 |
Supratentorial Brain | 0.0161 | <0.0001 | 0.0251 | 0.0009 | n.s. | <0.0001 | n.s. | 0.0002 |
Temporal Lobe (Left) | 0.0032 | <0.0001 | 0.0184 | 0.0013 | n.s. | <0.0001 | n.s. | 0.0002 |
Temporal Lobe (Right) | 0.0005 | <0.0001 | 0.0053 | 0.0009 | 0.0184 | <0.0001 | n.s. | <0.0001 |
Hippocampus (Left) | 0.0751 | <0.0001 | n.s. | 0.0025 | n.s. | <0.0001 | n.s. | 0.0001 |
Hippocampus (Right) | 0.0130 | <0.0001 | n.s. | 0.0016 | n.s. | <0.0001 | n.s. | <0.0001 |
Infratentorial Brain | 0.0002 | <0.0001 | n.s. | 0.0034 | n.s. | <0.0001 | n.s. | 0.0001 |