Table 3. Dosages of sedatives, incidence of delirium and patient-ventilator asynchrony, and mortality in SIMV + PS and A/C.
| Variables | SIMV + PS (n=20) | A/C (n=20) | P |
|---|---|---|---|
| Ventilator parameters | |||
| VT (mL/kg) | 7.0±0.5 | 6.9±0.8 | 0.489 |
| PEEP (cmH2O) | 8.7±3.0 | 10.3±3.2 | <0.001 |
| FiO2 (%) | 58±18 | 68±20 | <0.001 |
| Dosages of analgesics and sedatives | |||
| RASS | 2.4±1.6 | 2.6±1.3 | 0.128 |
| Fentanyl (mg) | 11.6±7.2 | 14.6±12.3 | 0.344 |
| Midazolam (mg) | 637.5±626.6 | 1145.0±1281.0 | 0.120 |
| Propofol (mg) | 6161.5±5788.3 | 3979.0±4313.9 | 0.184 |
| Duration of MV (d) | 15.3±11.8 | 15.3±12.1 | 1.000 |
| Delerium (%) | 0 (0.0) | 4 (20.0) | 0.106 |
| Patient-ventilator asynchrony (events/person) | 1.3±1.8 | 1.9±2.8 | 0.460 |
| Patient-ventilator asynchrony/duration of MV | 0.11±0.13 | 0.16±0.25 | 0.414 |
| In-hospital deaths (%) | 6 (30.0) | 8 (40.0) | 0.507 |
| ICU stay (d) | 22.4±13.6 | 19.6±14.9 | 0.537 |
| In-hospital stay (d) | 32.3±20.6 | 28.2±22.3 | 0.554 |
| ICU cost (RMB) | 124,750.0±91,271.2 | 115,690.0±132,840.0 | 0.803 |
| In-hospital cost (RMB) | 149,030.0±110,496.0 | 129,000.0±134,046.0 | 0.609 |
SIMV, synchronized intermittent mandatory ventilation; PS, pressure supportive; A/C, assist/control; VT, tidal volume; PEEP, positive end-expiratory pressure; FiO2, fraction of inspired oxygen; RASS, Richmond Agitation-Sedation Scale; MV, mechanical ventilation; ICU, intensive care unit.