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. 2016 Jan 7;7:247. doi: 10.3389/fnagi.2015.00247

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Copyright © 2016 Lin, Wu, Wu and Ko.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Results of the voxel-based morphometry of gray matter volume. The whole-brain exploratory analysis revealed significant activation at the right premotor cortex, the left dorsolateral prefrontal cortex, and the right precentral gyrus. The gray matter density of these regions was significantly positively correlated with masticatory performance. The scatter plots show the association between the masticatory performance index (ΔE) and the gray matter volume of each region. The masticatory performance index and gray matter volume were adjusted to remove the effects of age, gender, and total brain volume.