Table 4.
Parameter | Unit | Healthy | Infected |
---|---|---|---|
Emax | Log10CFU/mL | 2.35 | 2.91 |
E0 | Log10CFU/mL | −5.62 | −5.69 |
Emax−E0 | Log10CFU/mL | 7.97 | 8.60 |
EC50 | h | 348.51 | 802.26 |
Slope (N) | – | 2.85 | 2.72 |
AUC24/MIC for bacteriostatic action (E = 0) | h | 258.73 | 624.94 |
AUC24/MIC for bactericidal action (E = −3) | h | 451.35 | 1065.93 |
AUC24/MIC for bacterial eradication (E = −4) | h | 567.39 | 1343.81 |