Table 3.
List of genes showing reversed expression by Korean Red Ginseng in retina of rats with diabetes
| Description | Gene symbol | Fold change(DM/Con) | Fold change(DM+KRG/DM) |
|---|---|---|---|
| Adamts4 | ADAM metallopeptidase with thrombospondin type 1 motif, 4 | 5.704 | 0.336 |
| Adfp | Adipose differentiation related protein | 3.888 | 0.284 |
| Aldh3a1 | Aldehyde dehydrogenase 3 family, member A1 | 10.476 | 0.421 |
| Alox5ap | Arachidonate 5-lipoxygenase activating protein | 2.694 | 0.334 |
| Bcl3 | B-cell CLL/lymphoma 3 | 3.228 | 0.412 |
| Bfsp1 | Beaded filament structural protein 1 | 47.469 | 0.481 |
| Birc7 | Baculoviral IAP repeat-containing 7 | 4.274 | 0.312 |
| C1qb | Complement component 1, q subcomponent, B chain | 2.234 | 0.486 |
| C1qc | Complement component 1, q subcomponent, C chain | 3.839 | 0.455 |
| Ccnd2 | Cyclin D2 | 2.713 | 0.388 |
| Cd47 | Cd47 molecule | 2.248 | 0.495 |
| Cidea | Cell death-inducing DFFA-like effector a | 10.025 | 0.483 |
| Copg2 | Coatomer protein complex, subunit gamma 2 | 3.392 | 0.322 |
| Crip | Cysteine-rich intestinal protein | 2.590 | 0.499 |
| Cryga | Crystallin, gamma A | 4.765 | 0.368 |
| Crygb | Crystallin, gamma B | 62.504 | 0.397 |
| Crygc | Crystallin, gamma C | 78.570 | 0.483 |
| Crygd | Crystallin, gamma D | 83.967 | 0.415 |
| Cryge | Crystallin, gamma E | 5.100 | 0.301 |
| Cyp26a1 | Cytochrome P450, family 26, subfamily a, polypeptide 1 | 2.749 | 0.483 |
| Dclk1 | Doublecortin-like kinase 1 | 4.700 | 0.330 |
| Dennd4a | DENN/MADD domain containing 4A | 2.161 | 0.445 |
| Edn2 | Endothelin 2 | 10.581 | 0.208 |
| Emp1 | Epithelial membrane protein 1 | 4.698 | 0.357 |
| Fancb | Fanconi anemia, complementation group B | 4.804 | 0.386 |
| Fcgr2a | Fc fragment of IgG, low affinity IIa, receptor | 2.190 | 0.468 |
| Fgl2 | Fibrinogen-like 2 | 4.665 | 0.492 |
| Gadd45g | Growth arrest and DNA-damage-inducible, gamma | 3.838 | 0.345 |
| Gal | Galanin prepropeptide | 3.789 | 0.205 |
| Gfap | Glial fibrillary acidic protein | 12.043 | 0.482 |
| Gnb3 | Guanine nucleotide binding protein (G protein), beta polypeptide 3 | 2.735 | 0.382 |
| Gpnmb | Glycoprotein (transmembrane) nmb | 10.825 | 0.483 |
| Hmox1 | Heme oxygenase (decycling) 1 | 4.906 | 0.500 |
| Igf1r | Insulin-like growth factor 1 receptor | 2.000 | 0.490 |
| Il4ra | Interleukin 4 receptor, alpha | 2.750 | 0.252 |
| Inmt | Indolethylamine N-methyltransferase | 2.487 | 0.442 |
| Irak2 | Interleukin-1 receptor-associated kinase 2 | 2.669 | 0.210 |
| Kif11 | Kinesin family member 11 | 2.152 | 0.339 |
| Klf10 | Kruppel-like factor 10 | 2.202 | 0.378 |
| Krt12 | Keratin 12 | 41.472 | 0.263 |
| Krt18 | Keratin 18 | 3.840 | 0.343 |
| Krt6a | Similar to keratin complex 2, basic, gene 6a | 3.399 | 0.351 |
| Lcn2 | Lipocalin 2 | 16.957 | 0.434 |
| Lgals3 | Lectin, galactoside-binding, soluble, 3 | 40.062 | 0.372 |
| Litaf | Lipopolysaccharide-induced TNF factor | 4.198 | 0.441 |
| Lypd2 | Ly6/Plaur domain containing 2 | 7.488 | 0.297 |
| Matn2 | Matrilin 2 | 3.221 | 0.468 |
| Mlf1 | Myeloid leukemia factor 1 | 3.459 | 0.124 |
| Mmp14 | Matrix metallopeptidase 14 (membrane-inserted) | 2.255 | 0.487 |
| Mt1a | Metallothionein 1a | 10.301 | 0.493 |
| Mt2A | Metallothionein 2A | 18.029 | 0.433 |
| Muc3a | Mucin 3A, cell surface associated | 2.430 | 0.131 |
| Pdpn | Podoplanin | 3.687 | 0.430 |
| Plekha8 | Pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8 | 2.313 | 0.396 |
| Postn | Periostin, osteoblast specific factor | 2.090 | 0.387 |
| Prtg | Protogenin homolog (Gallus gallus) | 5.292 | 0.377 |
| S100a3 | S100 calcium binding protein A3 | 3.271 | 0.269 |
| Samd4a | Sterile alpha motif domain containing 4A | 4.179 | 0.487 |
| Sec16b | SEC16 homolog B (Saccharomyces cerevisiae) | 2.733 | 0.457 |
| Serpina3n | Serine (or cysteine) peptidase inhibitor, clade A, member 3N | 7.249 | 0.368 |
| Slc25a30 | Solute carrier family 25, member 30 | 2.251 | 0.348 |
| Slc26a8 | Solute carrier family 26, member 8 | 3.966 | 0.273 |
| Stat3 | Signal transducer and activator of transcription 3 | 3.115 | 0.397 |
| Stc1 | Stanniocalcin 1 | 2.472 | 0.497 |
| Tagln2 | Transgelin 2 | 3.708 | 0.461 |
| Tbata | Thymus, brain and testes associated | 2.623 | 0.468 |
| Timp1 | TIMP metallopeptidase inhibitor 1 | 11.742 | 0.282 |
| Tmbim1 | Transmembrane BAX inhibitor motif containing 1 | 5.420 | 0.388 |
| Tmod1 | Tropomodulin 1 | 3.865 | 0.407 |
| Cdr2 | Cerebellar degeneration-related 2 | 0.325 | 2.300 |
| Grk1 | G protein-coupled receptor kinase 1 | 0.409 | 2.307 |
| Herc3 | Hect domain and RLD 3 | 0.413 | 2.341 |
| Id3 | Inhibitor of DNA binding 3 | 0.574 | 2.263 |
| Lamb3 | Laminin, beta 3 | 0.200 | 2.333 |
| LOC689064 | Beta-globin | 0.264 | 2.262 |
| Pax4 | Paired box 4 | 0.436 | 4.471 |
| Pla2r1 | Phospholipase A2 receptor 1 | 0.408 | 2.520 |
| Prc1 | Protein regulator of cytokinesis 1 | 0.317 | 3.163 |
| RT1-S3 | RT1 class Ib, locus S3 | 0.449 | 2.086 |
| Sntg2 | Syntrophin, gamma 2 | 0.449 | 2.489 |
| Tmem116 | Transmembrane protein 116 | 0.439 | 2.533 |
| Trove2 | TROVE domain family, member 2 | 0.473 | 2.066 |