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Biomarkers indicative of lethal neurological RVF in Lewis rats.
| Biomarker | Time point (dpi) | |
|---|---|---|
| Cytokines/chemokines in serum: | ||
| ↑ RANTES | 1 | |
| ↑ MCP-1 | 3–5 | |
| ↑ M-CSF | 3–4 | |
| ↑ Gro/KC | 4 | |
| Blood cell parameters: | ||
| ↓ Lymphocytes | 3 | |
| ↑ Granulocytes | 4–7 | |
| ↓ Platelets | 4–7 | |
| Clinical indications: | ||
| Fever | 6–7 | |
| Weight loss | 6–7 | |
