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. 2016 Jan 7;6:1513. doi: 10.3389/fmicb.2015.01513

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Copyright © 2016 Zhou, Shi, Yu, Tao, Xiong, Sun and Liu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Relationships between the change in log₁₀ number of CFU for MRSA-M4 and PK/PD parameters of cefquinome. Each symbol represents the data from each catheter segment or tissue fluid. (A) T > MIC; (B) C_max/MIC; (C) AUC_24h/MIC; (D) T > MBIC; (E) C_max/MBIC; (F) AUC_24h/MBIC. The R² value is the determination coefficient. Data points below the horizontal line represent killing and points above the horizontal line represent growth. Planktonic cells, filled diamonds; biofilms, and open squares.