Table 2.
Transposon mutants permissive for Dictyostelium growth.
| Mutant No. | Genes inserted by transposon | Putative function | Homologs in M. tuberculosis H37Rv |
|---|---|---|---|
| 8-H11 | mmar_0328 | Secreted antigen 85-C | FpbC |
| 12-E12 | mmar_0838 | Hypothetical protein | |
| 14-C12 | mmar_0932 | PPE family protein | PPE24 |
| 14-F4 | mmar_1514 | PPE family protein, PPE51_1 | PPE51 |
| 12-B3, 12-E1 | Upstream of mmar_1594 and mmar_1595 | mmar_1594: PE_PGRS family protein mmar_1595:O-methyltransferase | PE_PGRS55 Rv3767c |
| 15-B4 | mmar_1639 | PPE family protein | PPE8 |
| 12-C12 | mmar_1887 | Conserved transmembrane transport protein | |
| 4-B11, 4-C3, 16-G9 | mmar_2313 | losA, glycosyltransferase | Rv1500 |
| 14-D5, 2-A3, 4-E9, 15-D8 | mmar_2318 | Conserved hypothetical protein | Rv1502 |
| 16-F5, 11-G3, 2-E6 | mmar_2319 | Conserved hypothetical transmembrane protein | |
| 2-C10, 2-G4 | mmar_2320 | wecE, pyridoxal phosphate-dependent enzyme | |
| 10-A11 | mmar_2323 | Conserved hypothetical transmembrane protein | |
| 13-B8 | mmar_2353 | UDP-glycosyltransferase | Rv1524 |
| 12-E11 | Upstream of mmar_2684 | PPE family protein | PPE32 |
| 18-G4 | mmar_3183 | Hypothetical alanine rich protein | |
| 18-D7 | Upstream of mmar_3375 | Conserved hypothetical protein | |
| 17-A5, 18-H5, 12-A1 | mmar_4263 | Conserved hypothetical protein | |
| 13-G8 | mmar_4621 | PPE family protein | PPE8 |
| 5-H1 | mmar_4630 | Membrane-bound C-5 sterol desaturase | Erg3 |