Table 1.
Anthropometric and biochemical variables in the two cohorts studied for mRNA and protein expression levels.
| First cohort |
Second cohort |
|||
|---|---|---|---|---|
| Lean | Obese | Lean | Obese | |
| N | 19 | 37 | 10 | 38 |
| Sex (male/female) | 13/6 | 22/15 | 5/5 | 16/22 |
| Age (years) | 51.68 ± 15.96 | 58.58 ± 13.21 | 42.90 ± 10.70 | 41.97 ± 11.91 |
| BMI (kg/m2) | 23.11 ± 1.59 | 29.07 ± 3.02a | 23.29 ± 1.33 | 42.39 ± 14.57a |
| Waist (cm) | 83.7 ± 7.9 | 99.29 ± 14.33a | 83.15 ± 6.78 | 116.22 ± 25.5a |
| DBP (mmHg) | 68.47 ± 9.90 | 76.4 ± 11.77b | 78.80 ± 19.62 | 79.14 ± 12.98 |
| SBP (mmHg) | 121.47 ± 11.77 | 135.84 ± 16.90b | 110.10 ± 21.94 | 131.11 ± 18.26a |
| Glucose (mmol/L) | 4.33 ± 0.68 | 5.56 ± 0.49a | 4.77 ± 0.63 | 5.19 ± 0.63 |
| Cholesterol (mmol/L) | 5.19 ± 1.18 | 5.10 ± 0.95 | 5.32 ± 1.06 | 5.12 ± 1.01 |
| HDLc (mmol/L) | 1.46 ± 0.21 | 1.35 ± 0.29 | 1.52 ± 0.39 | 1.26 ± 0.36 |
| Triglycerides (mmol/L) | 1.15 ± 0.53 | 1.17 ± 0.66 | 1.11 ± 0.58 | 1.45 ± 0.69 |
| Insulin (μIU/ml) | 4.52 ± 3.44 | 6.71 ± 4.94 | 6.75 ± 2.67 | 15.87 ± 11.56a |
| HOMA-IR | 1.11 ± 0.84 | 1.74 ± 1.35 | 1.40 ± 0.48 | 3.81 ± 2.83b |
The results are given as the mean ± SD. BMI: body mass index; DBP: Diastolic Blood Pressure; SBP: Systolic Blood Pressure. HOMA-IR: homeostasis model assessment of insulin resistance index. a indicate significant differences between the means of the different groups: a: p < 0.001: b: p < 0.01 (Student t test).