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Recommended Dosing Regimen for Ampicillin
| GA (weeks) |
PNA (days) |
Maintenance Dose (mg/kg) |
Dosing Interval (hours) |
|---|---|---|---|
| ≤ 34 | ≤ 7 | 50 | 12 |
| ≥ 8 and ≤ 28 | 75 | 12 | |
| > 34 | ≤ 28 | 50 | 8 |
GA: gestational age at birth; PNA: postnatal age
Data from Tremoulet A, Le J, Poindexter B, et al. Characterization of the Population Pharmacokinetics of Ampicillin in Neonates Using an Opportunistic Study Design. Antimicrob Agents Chemother 2014;58:3013–20.
