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Recommended Dosing Regimen for Meropenem
| GA (weeks) |
PNA (days) |
Maintenance Dose (mg/kg) |
Dosing Interval (hours) |
|---|---|---|---|
| < 32 | < 14 | 20 | 12 |
| ≥ 14 | 20 | 8 | |
| ≥ 32 | < 14 | ||
| ≥ 14 | 30 | 8 |
GA: gestational age at birth; PNA: postnatal age
Data from Smith PB, Cohen-Wolkowiez M, Castro LM, et al. Population pharmacokinetics of meropenem in plasma and cerebrospinal fluid of infants with suspected or complicated intra-abdominal infections. Pediatr Infect Dis J 2011;30:844–9
