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Recommended Dosing Regimen for Metronidazole
| PMA (weeks) |
Loading Dose (mg/kg) |
Maintenance Dose (mg/kg) |
Dosing Interval (hours) |
|---|---|---|---|
| < 34 | 15 | 7.5 | 12 |
| 34 – 40 | 8 | ||
| > 40 | 6 |
PMA: postmenstrual age
Data from Cohen-Wolkowiez M, Ouellet D, Smith PB, et al. Population pharmacokinetics of metronidazole evaluated using scavenged samples from preterm infants. Antimicrob Agents Chemother 2012;56:1828–37.
