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. 2015 Dec 28;19(4):220–227. doi: 10.5213/inj.2015.19.4.220

Fig. 4.

Fig. 4.

Modafinil increased the frequency and amplitude of spontaneous excitatory postsynaptic currents (sEPSCs) in CA1 pyramidal neurons in hippocampal slices. (A) Sample traces represent sEPSCs recorded in a CA1 pyramidal neuron during 1mM modafinil treatment. (B) Modafinil increased the frequency of sEPSCs (n=9, P<0.01). (C) Cumulative amplitude distribution of sEPSCs shows that modafinil increased the amplitude of sEPSCs (n=9, Kolmogorov-Smirnov test, P<0.01). Membrane holding potential, –70 mV. **P<0.01 compared with the control group.