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. 2015 Dec 28;19(4):220–227. doi: 10.5213/inj.2015.19.4.220

Fig. 5.

Fig. 5.

Modafinil decreased the frequency and amplitude of spontaneous inhibitory postsynaptic currents (sIPSCs) in CA1 pyramidal neurons in hippocampal slices. (A) Sample traces represent sIPSCs recorded in a CA1 pyramidal neuron during 1mM modafinil treatment. (B) Modafinil decreased the frequency of sIPSCs (n=8, P<0.01). (C) Cumulative amplitude distribution of sIPSCs shows that modafinil decreased the amplitude of sIPSCs (n=8, Kolmogorov-Smirnov test, P<0.01). Membrane holding potential, –10 mV. **P<0.01 compared with the control group.