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. 2016 Jan 7;6:18880. doi: 10.1038/srep18880

Table 1. Kinetic parameters of Mtb HspAT and ArAT.

mHspAT aminotransferase activity Hsp Phe Tyr
KM[mM] 0.42 ± 0.02 7.1 ± 0.81 9.76 ± 0.69
kcat[s−1] (4.26 ± 0.31) × 102 (2.2 ± 0.13) × 102 (3.1 ± 0.26) × 103
kcat/KM [M−1s−1] (1.02 ± 0.087) × 106 (3.0 ± 0.3) × 104 (3.2 ± 0.35) × 105
mArAT aminotransferase activity Phe Tyr Trp
KM[mM] 0.036 ± 0.001 0.86 ± 0.05 6.26 ± 0.43
kcat[s−1] (3.5 ± 0.14) × 102 (2.78 ± 0.09) × 102 (9.6 ± 0.64) × 102
kcat/KM [M−1s−1] (9.7 ± 0.47) × 106 (3.2 ± 0.21) × 105 (1.54 ± 0.14) × 105