TABLE 1.
Antibiotic MICs and BICs for Achromobacter CF isolates measured by planktonic and biofilm susceptibility testing
| MIC/BIC by antibiotic | Results for Achromobacter species |
||
|---|---|---|---|
| All species (n = 68) | A. xylosoxidans (n = 50) | Other species (n = 18)a | |
| Amikacin | |||
| MIC50 | 512 | 1,024 | 256 |
| BIC50 | >4,096 | >4,096 | >4,096 |
| MIC90 | >4,096 | >4,096 | >4,096 |
| BIC90 | >4,096 | >4,096 | >4,096 |
| Aztreonam | |||
| MIC50 | 256 | 512 | 512 |
| BIC50 | >2,048 | >2,048 | >2,048 |
| MIC90 | 2,048 | 2,048 | 2,048 |
| BIC90 | >2,048 | >2,048 | >2,048 |
| Colistin | |||
| MIC50 | 4 | 8 | 4 |
| BIC50 | >256 | >256 | >256 |
| MIC90 | 64 | 64 | 64 |
| BIC90 | >256 | >256 | >256 |
| Levofloxacin | |||
| MIC50 | 20 | 20 | 20 |
| BIC50 | 5,120 | 5,120 | 5,120 |
| MIC90 | 20 | 20 | 20 |
| BIC90 | >5,120 | >5,120 | >5,120 |
| Tobramycin | |||
| MIC50 | 200 | 400 | 200 |
| BIC50 | 3,200 | 3,200 | 3,200 |
| MIC90 | >3,200 | >3,200 | >3,200 |
| BIC90 | >3,200 | >3,200 | >3,200 |
a
“Other species” includes A. denitrificans (n = 3), A. dolens (n = 5), A. insolitus (n = 5), and A. ruhlandii (n = 5).